Phytochemical profile, total phenolic content and antioxidant activity of ethanolic extract of fumitory (Fumaria capreolata L.) from Algeria

  • Ismahene Sofiane Plant Biology and Environment Laboratory, “Medicinal Plants” Axis, Biology Department, Faculty of Sciences, BADJI Mokhtar - Annaba University, Bp 12, 23000 Annaba, Algeria
  • Ratiba Seridi Plant Biology and Environment Laboratory, “Medicinal Plants” Axis, Biology Department, Faculty of Sciences, BADJI Mokhtar - Annaba University, Bp 12, 23000 Annaba, Algeria
Keywords: Fumaria capreolata L., Phytochemical screening, Antioxidant activity, DPPH, β-carotene, FRAP


Fumitory or Fumaria capreolata L. is a medicinal plant, spontaneous and widely distributed in North Africa, particularly in Algeria. It has been recognized for centuries for its therapeutic virtues, and it is used in traditional medicine in the treatment of hepatobiliary diseases, gastrointestinal disorders and in the treatment of skin diseases. The phytochemical screening carried out on the aerial part of the species F. capreolata L., revealed the richness of this plant in secondary metabolites, such as alkaloids, catechic tannins, sterols and terpenes. On the other hand, we noticed the absence of cardinolides, leuco-anthocyanins, quinones and starch in all parts of the plant. Quantitative spectrophotometric analysis allowed us to detect the levels of total polyphenols using the reagent of Folin-Ciocalteu, according to the results obtained we find that the species F. capreolata is rich in these compounds (14.27 ± 1.65 mg GAE/g). The evaluation of the antioxidant activity was carried out using the DPPH method, indicated that the ethanolic extract of F. capreolata L. showed significant antioxidant activity, with an IC50 = 0.27 mg/ml. And it also has a strong inhibitory activity of the coupled oxidation of linoleic acid and β-carotene, with a percentage of 88.46 ± 1.02% at a concentration of 0.5 mg/ml. In addition, the crude extract of F. capreolata L., also exhibits a good iron reduction capacity, with a maximum optical density of 0.349 at a concentration of 0.5 mg/ml.



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How to Cite
Sofiane, I.; Seridi, R. Phytochemical Profile, Total Phenolic Content and Antioxidant Activity of Ethanolic Extract of Fumitory (Fumaria Capreolata L.) from Algeria. European Journal of Biological Research 2021, 11, 404-416.
Research Articles