Polyhexanide (PHMB) – properties and applications in medicine

  • Patrycja Szkołuda Student Scientific Club of Medical Microbiology, Chair and Department of Medical Microbiology, Poznań University of Medical Sciences, Wieniawskiego 3, 61-712, Poznań, Poland
  • Tomasz M. Karpiński Chair and Department of Medical Microbiology, Poznań University of Medical Sciences, Wieniawskiego 3, 61-712, Poznań, Poland https://orcid.org/0000-0001-6599-9204
Keywords: Polyhexanide, PHMB, Polyhexamethylene biguanide, Antiseptic, Antimicrobial, Wound


Polyhexamethylene biguanide (PHMB) is one of the many antiseptics available in the medicine. It stands out from the others with its numerous advantages. It has a low toxicity factor, chemical stability, and bactericidal effect on most microorganisms. PHMB is used in many areas of medicine, veterinary medicine, gastronomy, and industry. The application of polyhexanide in the treatment of chronic wounds allows for fast regeneration and reduced time of wound treatment and hospitalization. According to the Recommendations of the Polish Wound Treatment Society, PHMB is recommended in treatment of critically colonized wounds, wounds at risk infection, burns, and decontamination of acute and chronic wounds, and as second choice in infected wounds.

DOI: http://dx.doi.org/10.5281/zenodo.3956819


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