Women are more susceptible than men to micronutrient depletion during petrol exposure

Ayobola A. Iyanda, John Anetor


The influence of gender on the modulating effects of many xenobiotics has been suggested. The aim of the study is to determine which of the genders, is more at risk of altered micronutrient status subsequent to petroleum-product exposure. 60 petrol-station attendants (PSA) as well as 60 control participants were recruited for the study. The test or control group for each gender consisted of 30 participants. Serum obtained from five millimeters of blood was used to determine the levels of micronutrients. Vitamins and trace elements were determined using High Performance Liquid Chromatography and Atomic Absorption Spectrometry respectively. Significant differences between groups were ascertained using Student’s t test. Correlation study between length of service (at petrol station) and micronutrient levels was determined using Pearson’s correlation co-efficient. P<0.05 was considered significant. Although correlation was observed between length of service and several micronutrients for both male and female PSA and petrol caused significant reduction in micronutrient levels in both groups of PSA; Mo, Fe and Se, pyridoxine, niacin, vitamins E and vitamin C were more significantly lower in female PSA than male ones. These results suggest that women are more susceptible than men to micronutrient depletion during petrol exposure.


Male; Female; Vitamins; Minerals; Petrol station attendants

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