Alteration in biochemical indices following administration of seafood (Thais coronata) extract

Archibong Nsa Archibong, Ada A. Akwari, Ofem Effiong Ofem, Irene O. Bassey, S. U. Ukweni, Asim Ekaha Eno

Abstract


Seafood consumption has been a way of life to most people especially those that leave in riverine areas, because seafoods are known to contain many nutrients that are essential for healthy living. Consequently, this research therefore seeks to investigate the effect of these nutritive components of Thais coronata on biochemical indices of albino Wistar rats. Fourty five male albino Wister rats weighing between 180-220 g were assigned into 3 groups of fifteen rats each in metabolic cages and were given rat feed and drinking water ad libitum. Two test doses (low dose 7.0 mg protein/ml and  high dose 52 mg protein/ml) were selected  and  administered  to  two  groups  of  rats  orally  and  daily  for  six  weeks,  while  a third group of rats served as the control, n = 15. At the expiration of the feeding period, blood samples were obtained from all the rats via cardiac puncture for the analysis of the various biochemical indices. Both the low and high doses of the extract produced significant increases in HDLc (P<0.001) compared with control. k (P<0.001), HCO3- (P<0.01) and Ca2+ (P<0.001) were also significantly increased in the  extract treated groups. The extract groups had significant reductions in ALT (P<0.001), ALP (P<0.001), Na+ (P<0.001) and Cl- (P<0.001) compared with control. Also Tc (P<0.001), TG (P<0.001), LDL (P<0.001) and VLDLc (P<0.001) were significantly decreased in the extract treated group. In conclusion seafood consumption is of immense benefit to health because it serves to regulate the lipid profile, electrolytes and enzyme concentrations in blood.


Keywords


Rock snail; Thais coronata; Biochemical indices; Vitamin; Omega-3 fatty acid

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References


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