Marine biomolecules: a promising approach in therapy and biotechnology
Keywords:
Marine biomolecules, Biofilms, Health issues, Aquaculture
Abstract
The marine environment is characterized by a wide diversity of microorganisms among which marine bacteria. To insure their survival in hostile conditions where they face high competition with pathogenic microorganisms, they produce various kinds of bioactive molecules within biofilms with unique structural and functional features. As example: marine peptides which provide a broad spectrum of antimicrobial, antitumoral, antiviral and anti-inflammatory activities, in addition to marine exopolysaccharides showing antifouling and antifungal activities, immunomodulatory properties, emulsion stabilization capacity with other various potentials. Some biofilms have shown a beneficial role for aquaculture, among which enhancement of growth performance and improvement of water quality, while others are threatening not only aquaculture and maritime fields, but also medicine and food industry. Thus, marine bioactive compounds are promising preventing agents for the establishment and growth of fouling microorganisms, which may be useful in different fields in order to decrease economic losses and avoid foodborne illnesses.
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References
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28. Kokoulin MS, Kuzmich AS, Romanenko LA, Menchinskaya ES, Mikhailov VV, Chernikov OV. Sulfated O-polysaccharide with anticancer activity from the marine bacterium Poseidonocella sedimentorum KMM 9023T. Carbohydr Polym. 2018; 202: 157-163.
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31. Hussain A, Zia KM, Tabasum S, Noreen A, Ali M, Iqbal R, Zuber M. Blends and composites of exopolysaccharides; properties and applications: a review. Int J Biol Macromol. 2017; 94: 10-27.
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33. Rodrigues S, Paillard C, Dufour A, Bazire A. Antibiofilm activity of the marine bacterium Pseudoalteromonas sp. 3J6 against Vibrio tapetis, the causative agent of Brown Ring Disease. Probiotics Antimicr Proteins. 2014; 7: 45-51.
34. Klein GL, Soum-Soutéra E, Guede Z, Bazire A, Compère C, Dufour A. The anti-biofilm activity secreted by a marine Pseudoalteromonas strain. Biofouling. 2011; 27: 931-940.
35. Satheesh S, Ba-Akdah MA, Al-Sofyani AA. Natural antifouling compound production by microbes associated with marine macroorganisms – a review. Electr J Biotechnol. 2016; 21: 26-35.
36. Tortorella E, Tedesco P, Esposito FP, January GG, Fani R, Jaspars M, De Pascale D. Antibiotics from deep-sea microorganisms: Current discoveries and perspectives. Mar Drugs. 2018; 16: 1-16.
37. Liaw CC, Chen PC, Shih CJ, Tseng SP, Lai YM, Hsu CH, et al. Vitroprocines, new antibiotics against Acinetobacter baumannii, discovered from marine Vibrio sp. QWI-06 using mass-spectrometry-based metabolomics approach. Sci Rep. 2015; 5: 1-11.
38. Sutherland IW. The biofilm matrix - an immobilized but dynamic microbial environment. Trends Microbiol. 2001; 9: 222-227.
39. Jorquera MA, Riquelme CE, Loyola LA, Muñoz LF. Production of bactericidal substances by a marine vibrio isolated from cultures of the scallop Argopecten purpuratus. Aquac Int. 2000; 7: 433-448.
40. Satheesh S, Ba-Akdah MA, Al-Sofyani AA. Natural antifouling compound production by microbes associated with marine macroorganisms - a review. Electron J Biotechnol. 2016; 21: 26-35.
41. Mohan K, Ravichandran S, Muralisankar T, Uthayakumar V, Chandirasekar R, Seedevi P, et al. Application of marine-derived polysaccharides as immunostimulants in aquaculture: A review of current knowledge and further perspectives. Fish Shellfish Immunol. 2019; 86: 1177-1193.
42. Qian PY, Lau SCK, Dahms HU, Dobretsov S, Harder T. Marine biofilms as mediators of colonization by marine macroorganisms: Implications for antifouling and aquaculture. Mar Biotechnol. 2007; 9: 399-410.
43. Pradeep B, Pandey PK, Ayyappan S. Effect of probiotic and antibiotics on water quality and bacterial flora. J Inland Fish Soc India. 2003; 35(2): 68-72.
44. Mizan MFR, Jahid IK, Ha SD. Microbial biofilms in seafood: A food-hygiene challenge. Food Microbiol. 2015; 49: 41-55.
45. Radford S, States U. Sources of contamination in food. Encyclopedia of Food Security and Sustainability. Elsevier. 2018.
46. Vitale M, Schillaci D. Food processing and foodborne illness. In: Reference Module in Food Science. Elsevier. 2016; 1-9.
47. Cole DW, Cole R, Gaydos SJ, Gray J, Hyland G, Jacques ML, et al. Aquaculture: environmental, toxicological, and health issues. Int J Hyg Environ Health. 2009; 212: 369-377.
48. Yebra DM, Kiil S, Dam-Johansen K. Antifouling technology - past, present and future steps towards efficient and environmentally friendly antifouling coatings. Prog Org Coat. 2004; 50: 75-104.
49. Fusetani N. Biofouling and antifouling. Nat Prod Rep. 2004; 21: 94-104.
50. Hamza F, Satpute S, Banpurkar A, Kumar AR, Zinjarde S. Biosurfactant from a marine bacterium disrupts biofilms of pathogenic bacteria in a tropical aquaculture system. FEMS Microbiol Ecol. 2017; 93: 1-11.
2. Jimeno J, Faircloth G, Sousa-Faro J, Scheuer P, Rinehart K. New marine derived anticancer therapeutics. A journey from the sea to clinical trials. Mar Drugs. 2004; 2: 14-29.
3. Guezennec J. Deep-sea hydrothermal vents: A new source of innovative bacterial exopolysaccharides of biotechnological interest. J Ind Microbiol Biotechnol. 2002; 29: 204-208.
4. Hall-Stoodley L, Costerton JW, Stoodley P. Bacterial biofilms: from the natural environment to infectious diseases. Nat Rev Microbiol. 2004; 2: 95-108.
5. Panday PK, Vivekanand B, Kundan K. Biofilm in aquaculture production. Afr J Microbiol Res. 2014;
8: 1434-1443.
6. Wahl M, Goecke F, Labes A, Dobretsov S, Weinberger F. The second skin: ecological role of epibiotic biofilms on marine organisms. Front Microbiol. 2012; 3: 1-21.
7. Walsh EA, Kirkpatrick JB, Rutherford SD, Smith DC, Sogin M, D’Hondt S. Bacterial diversity and community composition from seasurface to subseafloor. ISME J. 2016; 10: 979-989.
8. Taylor P, Tiquia SM, Davis D, Hadid H, Kasparian S, Ismail M, et al. Halophilic and halotolerant bacteria from river waters and shallow groundwater along the Rouge River of Southeastern Michigan. Environ Technol. 2010; 37-41.
9. Csonka LN. Physiological and genetic responses of bacteria to osmotic stress. Microbiol Rev. 1989; 53: 121-147.
10. Karpiński TM. Marine macrolides with antibacterial and/or antifungal activity. Mar Drugs. 2019; 17(4): 241.
11. Letchumanan V, Chan KG, Lee LH. Vibrio parahaemolyticus: a review on the pathogenesis, prevalence, and advance molecular identification techniques. Front Microbiol. 2014; 5: 1-13.
12. Gozari M, Alborz M, El-Seedi HR, Jassbi AR. Chemistry, biosynthesis and biological activity of terpenoids and meroterpenoids in bacteria and fungi isolated from different marine habitats. Eur J Med Chem. 2020; 112957.
13. Lafarga T, Acién-Fernández FG, Garcia-Vaquero M. Bioactive peptides and carbohydrates from seaweed for food applications: Natural occurrence, isolation, purification, and identification. Algal Res. 2020; 48: 101909.
14. Ganesan AR, Saravana Guru M, Balasubramanian B, Mohan K, Chao Liu W, Valan Arasu M, et al. Biopolymer from edible marine invertebrates: a potential functional food. J King Saud Univ Sci. 2020; 32: 1772-1777.
15. Rizzo C, Lo Giudice A. Marine invertebrates: underexplored sources of bacteria producing biologically active molecules. Diversity. 2018; 10: 52.
16. Jimenez-Lopez C, Pereira AG, Lourenço-Lopes C, Garcia-Oliveira P, Cassani L, Fraga-Corral, M, et al. Main bioactive phenolic compounds in marine algae and their mechanisms of action supporting potential health benefits. Food Chem. 2021; 341: 128262.
17. Hannan MA, Sohag AAM, Dash R, Haque MN, Mohibbullah M, Oktaviani DF, et al. Phytosterols of marine algae: Insights into the potential health benefits and molecular pharmacology. Phytomedicine. 2020; 69: 153201.
18. Selvin J, Lipton AP. Biopotentials of secondary metabolites isolated from marine sponges. Hydrobiologia. 2004; 513: 231-238.
19. Anjum K, Abbas SQ, Shah SAA, Akhter N, Batool S, Hassan SSU. Marine sponges as a drug treasure. Biomol Ther. 2016; 24: 347-362.
20. Tourón N, Elkhalfi B, Yassine SM, Chabir R, Errachidi F, Abdelaziz S. Rheological and antioxidant characterization of chitin and chitosan extracted with different acids. J Chitin Chitosan Sci. 2016; 4 (1): 41-45.
21. Tamadoni Jahromi S, Barzkar N. Marine bacterial chitinase as sources of energy, ecofriendly agent, and industrial biocatalyst. Int J Biol Macromol. 2018; 20: 2147-2154.
22. Murray PM, Moane S, Collins C, Beletskaya T, Thomas OP, Duarte AWF, et al. Sustainable production of biologically active molecules of marine based origin. N Biotechnol. 2013; 30: 839-850.
23. Bernstein PS. The role of lutein and zeaxanthin in protection against age-related macular degeneration. Acta Horticulturae. 2015; 1106: 153-159.
24. Murillo AG, Hu S, Fernandez ML. Zeaxanthin: metabolism, properties, and antioxidant protection of eyes, heart, liver, and skin. Antioxidants. 2019; 8: 1-18
25. Suseela MR, Kiran T. Haematococcus pluvialis - a green alga, richest natural source of astaxanthin. Curr Sci. 2006; 90(12): 1602-1603.
26. Fakhri S, Aneva IY, Farzaei MH Sobarzo-Sánchez E. The neuroprotective effects of astaxanthin: Therapeutic targets and clinical perspective. Molecules. 2019; 24: 1-19.
27. Karpiński TM, Adamczak A. Fucoxanthin - an antibacterial carotenoid. Antioxidants. 2019; 8(8): 239.
28. Kokoulin MS, Kuzmich AS, Romanenko LA, Menchinskaya ES, Mikhailov VV, Chernikov OV. Sulfated O-polysaccharide with anticancer activity from the marine bacterium Poseidonocella sedimentorum KMM 9023T. Carbohydr Polym. 2018; 202: 157-163.
29. Kokoulin MS, Kuzmich AS, Kalinovsky AI, Tomshich SV, Romanenko LA, Mikhailov VV, et al. Structure and anticancer activity of sulfated O-polysaccharide from marine bacterium Cobetia litoralis KMM 3880T. Carbohydr Polym. 2016; 154: 55-61.
30. Ruocco N, Costantini S, Guariniello S, Costantini M. Polysaccharides from the marine environment with pharmacological, cosmeceutical and nutraceutical potential. Molecules. 2016; 21: 1-16.
31. Hussain A, Zia KM, Tabasum S, Noreen A, Ali M, Iqbal R, Zuber M. Blends and composites of exopolysaccharides; properties and applications: a review. Int J Biol Macromol. 2017; 94: 10-27.
32. Wang KL, Wu ZH, Wang Y, Wang CY, Xu Y. Mini-review : antifouling natural products from marine microorganisms and their synthetic analogs. Mar Drugs. 2017; 15: 266.
33. Rodrigues S, Paillard C, Dufour A, Bazire A. Antibiofilm activity of the marine bacterium Pseudoalteromonas sp. 3J6 against Vibrio tapetis, the causative agent of Brown Ring Disease. Probiotics Antimicr Proteins. 2014; 7: 45-51.
34. Klein GL, Soum-Soutéra E, Guede Z, Bazire A, Compère C, Dufour A. The anti-biofilm activity secreted by a marine Pseudoalteromonas strain. Biofouling. 2011; 27: 931-940.
35. Satheesh S, Ba-Akdah MA, Al-Sofyani AA. Natural antifouling compound production by microbes associated with marine macroorganisms – a review. Electr J Biotechnol. 2016; 21: 26-35.
36. Tortorella E, Tedesco P, Esposito FP, January GG, Fani R, Jaspars M, De Pascale D. Antibiotics from deep-sea microorganisms: Current discoveries and perspectives. Mar Drugs. 2018; 16: 1-16.
37. Liaw CC, Chen PC, Shih CJ, Tseng SP, Lai YM, Hsu CH, et al. Vitroprocines, new antibiotics against Acinetobacter baumannii, discovered from marine Vibrio sp. QWI-06 using mass-spectrometry-based metabolomics approach. Sci Rep. 2015; 5: 1-11.
38. Sutherland IW. The biofilm matrix - an immobilized but dynamic microbial environment. Trends Microbiol. 2001; 9: 222-227.
39. Jorquera MA, Riquelme CE, Loyola LA, Muñoz LF. Production of bactericidal substances by a marine vibrio isolated from cultures of the scallop Argopecten purpuratus. Aquac Int. 2000; 7: 433-448.
40. Satheesh S, Ba-Akdah MA, Al-Sofyani AA. Natural antifouling compound production by microbes associated with marine macroorganisms - a review. Electron J Biotechnol. 2016; 21: 26-35.
41. Mohan K, Ravichandran S, Muralisankar T, Uthayakumar V, Chandirasekar R, Seedevi P, et al. Application of marine-derived polysaccharides as immunostimulants in aquaculture: A review of current knowledge and further perspectives. Fish Shellfish Immunol. 2019; 86: 1177-1193.
42. Qian PY, Lau SCK, Dahms HU, Dobretsov S, Harder T. Marine biofilms as mediators of colonization by marine macroorganisms: Implications for antifouling and aquaculture. Mar Biotechnol. 2007; 9: 399-410.
43. Pradeep B, Pandey PK, Ayyappan S. Effect of probiotic and antibiotics on water quality and bacterial flora. J Inland Fish Soc India. 2003; 35(2): 68-72.
44. Mizan MFR, Jahid IK, Ha SD. Microbial biofilms in seafood: A food-hygiene challenge. Food Microbiol. 2015; 49: 41-55.
45. Radford S, States U. Sources of contamination in food. Encyclopedia of Food Security and Sustainability. Elsevier. 2018.
46. Vitale M, Schillaci D. Food processing and foodborne illness. In: Reference Module in Food Science. Elsevier. 2016; 1-9.
47. Cole DW, Cole R, Gaydos SJ, Gray J, Hyland G, Jacques ML, et al. Aquaculture: environmental, toxicological, and health issues. Int J Hyg Environ Health. 2009; 212: 369-377.
48. Yebra DM, Kiil S, Dam-Johansen K. Antifouling technology - past, present and future steps towards efficient and environmentally friendly antifouling coatings. Prog Org Coat. 2004; 50: 75-104.
49. Fusetani N. Biofouling and antifouling. Nat Prod Rep. 2004; 21: 94-104.
50. Hamza F, Satpute S, Banpurkar A, Kumar AR, Zinjarde S. Biosurfactant from a marine bacterium disrupts biofilms of pathogenic bacteria in a tropical aquaculture system. FEMS Microbiol Ecol. 2017; 93: 1-11.
Published
2020-12-22
How to Cite
(1)
Chbel, A.; Delgado, A.; Soukri, A.; El Khalfi, B. Marine Biomolecules: A Promising Approach in Therapy and Biotechnology. European Journal of Biological Research 2020, 11, 122-133.
Section
Review Articles
This work is licensed under a Creative Commons Attribution 4.0 International License.
